Items where Division is "Melanoma Oncology and Immunology"

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Alavi, Sara and Emran, Abdullah Al and Tseng, Hsin-Yi and Tiffen, Jessamy C. and McGuire, Helen Marie and Hersey, Peter Nicotinamide Inhibits T Cell Exhaustion and Increases Differentiation of CD8 Effector T Cells. Cancers (2022), 14 (2) p. 323. ISSN 2072-6694

Ahmed, Farzana and Tseng, Hsin-Yi and Ahn, Antonio and Gunatilake, Dilini and Alavi, Sara and Eccles, Michael and Rizos, Helen and Gallagher, Stuart J and Tiffen, Jessamy C and Hersey, Peter and Emran, Abdullah Al Repurposing Melanoma Chemotherapy to Activate Inflammasomes in the Treatment of BRAF/MAPK Inhibitor Resistant Melanoma. Journal of Investigative Dermatology (2021), 142 (5) 1444-1455.e10. ISSN 0022202X

Ahn, Antonio and Rodger, Euan J. and Motwani, Jyoti and Gimenez, Gregory and Stockwell, Peter A. and Parry, Matthew and Hersey, Peter and Chatterjee, Aniruddha and Eccles, Michael R. Transcriptional Reprogramming and Constitutive PD-L1 Expression in Melanoma Are Associated with Dedifferentiation and Activation of Interferon and Tumour Necrosis Factor Signalling Pathways. Cancers (2021), 13 (17) p. 4250. ISSN 2072-6694

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Cebon, Jonathan S and Gore, Martin and Thompson, John F and Davis, Ian D and McArthur, Grant A and Walpole, Euan and Smithers, Mark and Cerundolo, Vincenzo and Dunbar, P Rod and MacGregor, Duncan and Fisher, Cyril and Millward, Michael and Nathan, Paul and Findlay, Michael P N and Hersey, Peter and Evans, T R Jeffry and Ottensmeier, Christian Hermann and Marsden, Jeremy and Dalgleish, Angus G and Corrie, Pippa G and Maria, Marples and Brimble, Margaret and Williams, Geoff and Winkler, Sintia and Jackson, Heather M and Endo-Munoz, Liliana and Tutuka, Candani S A and Venhaus, Ralph and Old, Lloyd J and Haack, Dennis and Maraskovsky, Eugene and Behren, Andreas and Chen, Weisan Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma. Journal for ImmunoTherapy of Cancer (2020), 8 (1) e000410. ISSN 2051-1426

Chatterjee, Aniruddha and Rodger, Euan J. and Ahn, Antonio and Stockwell, Peter A. and Parry, Matthew and Motwani, Jyoti and Gallagher, Stuart J. and Shklovskaya, Elena and Tiffen, Jessamy and Eccles, Michael R. and Hersey, Peter Marked Global DNA Hypomethylation Is Associated with Constitutive PD-L1 Expression in Melanoma. iScience (2018), 4 pp. 312-325. ISSN 25890042

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Dizier, Benjamin and Callegaro, Andrea and Debois, Muriel and Dreno, Brigitte and Hersey, Peter and Gogas, Helen J. and Kirkwood, John M. and Vansteenkiste, Johan F. and Sequist, Lecia V. and Atanackovic, Djordje and Goeman, Jelle and van Houwelingen, Hans and Salceda, Susana and Wang, Fawn and Therasse, Patrick and Debruyne, Channa and Spiessens, Bart and Brichard, Vincent G. and Louahed, Jamila and Ulloa-Montoya, Fernando A Th1/IFNγ Gene Signature Is Prognostic in the Adjuvant Setting of Resectable High-Risk Melanoma but Not in Non–Small Cell Lung Cancer. Clinical Cancer Research (2019), 26 (7) pp. 1725-1735. ISSN 1078-0432

Dreno, Brigitte and Thompson, John F and Smithers, Bernard Mark and Santinami, Mario and Jouary, Thomas and Gutzmer, Ralf and Levchenko, Evgeny and Rutkowski, Piotr and Grob, Jean-Jacques and Korovin, Sergii and Drucis, Kamil and Grange, Florent and Machet, Laurent and Hersey, Peter and Krajsova, Ivana and Testori, Alessandro and Conry, Robert and Guillot, Bernard and Kruit, Wim H J and Demidov, Lev and Thompson, John A and Bondarenko, Igor and Jaroszek, Jaroslaw and Puig, Susana and Cinat, Gabriela and Hauschild, Axel and Goeman, Jelle J and van Houwelingen, Hans C and Ulloa-Montoya, Fernando and Callegaro, Andrea and Dizier, Benjamin and Spiessens, Bart and Debois, Muriel and Brichard, Vincent G and Louahed, Jamila and Therasse, Patrick and Debruyne, Channa and Kirkwood, John M MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial. The Lancet Oncology (2018), 19 (7) pp. 916-929. ISSN 14702045

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Emran, Abdullah Al and Tseng, Hsin-Yi and Gunatilake, Dilini and Cook, Stuart J. and Ahmed, Farzana and Wang, Shudong and Hersey, Peter and Gallagher, Stuart J. and Tiffen, Jessamy C. A Combination of Epigenetic BET and CDK9 Inhibitors for Treatment of Human Melanoma. Journal of Investigative Dermatology (2021), 141 (9) 2238-2249.e12. ISSN 0022202X

Emran, Abdullah Al and Gallagher, Stuart J. and Tiffen, Jessamy C. and Hersey, Peter Sex bias of females in survival from cancer and infections. Is X the answer? [Editorial Material]

Emran, Abdullah Al and Tseng, Hsin‐Yi and Coleman, Mikaela C. and Tiffen, Jessamy and Cook, Stuart and McGuire, Helen M. and Gallagher, Stuart and Feng, Carl and Hersey, Peter Do innate killing mechanisms activated by inflammasomes have a role in treating melanoma? [Review]

Emran, Abdullah Al and Nsengimana, Jérémie and Punnia-Moorthy, Gaya and Schmitz, Ulf and Gallagher, Stuart J. and Newton-Bishop, Julia and Tiffen, Jessamy C. and Hersey, Peter Study of the Female Sex Survival Advantage in Melanoma—A Focus on X-Linked Epigenetic Regulators and Immune Responses in Two Cohorts. Cancers (2020), 12 (8) p. 2082. ISSN 2072-6694

Emran, Abdullah Al and Marzese, Diego M and Menon, Dinoop R and Hammerlindl, Heinz and Ahmed, Farzana and Richtig, Erika and Duijf, Pascal and Hoon, Dave SB and Schaider, Helmut Commonly integrated epigenetic modifications of differentially expressed genes lead to adaptive resistance in cancer. Epigenomics (2019), 11 (7) pp. 732-737. ISSN 1750-1911

Emran, Abdullah Al and Chinna Chowdary, Brinda Reddy and Ahmed, Farzana and Hammerlindl, Heinz and Huefner, Antje and Haass, Nikolas K. and Schuehly, Wolfgang and Schaider, Helmut Magnolol induces cell death through PI3K/Akt‐mediated epigenetic modifications boosting treatment of BRAF‐ and NRAS ‐mutant melanoma. Cancer Medicine (2019), 8 (3) pp. 1186-1196. ISSN 2045-7634

Emran, Abdullah Al and Chatterjee, Aniruddha and Rodger, Euan J. and Tiffen, Jessamy C. and Gallagher, Stuart J. and Eccles, Michael R. and Hersey, Peter Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy. Trends in Immunology (2019), 40 (4) pp. 328-344. ISSN 14714906

Edwards, Jarem and Wilmott, James S. and Madore, Jason and Gide, Tuba Nur and Quek, Camelia and Tasker, Annie and Ferguson, Angela and Chen, Jinbiao and Hewavisenti, Rehana and Hersey, Peter and Gebhardt, Thomas and Weninger, Wolfgang and Britton, Warwick J. and Saw, Robyn P.M. and Thompson, John F. and Menzies, Alexander M. and Long, Georgina V. and Scolyer, Richard A. and Palendira, Umaimainthan CD103+Tumor-Resident CD8+T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti–PD-1 Treatment. Clinical Cancer Research (2018), 24 (13) pp. 3036-3045. ISSN 1078-0432

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Gallagher, Stuart J. and Gunatilake, Dilini and Beaumont, Kimberley A. and Sharp, Danae M. and Tiffen, Jessamy C. and Heinemann, Anja and Weninger, Wolfgang and Haass, Nikolas K. and Wilmott, James S. and Madore, Jason and Ferguson, Peter M. and Rizos, Helen and Hersey, Peter HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. International Journal of Cancer (2017), 142 (9) pp. 1926-1937. ISSN 00207136

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Hersey, Peter Re: Pyrexia in patients treated with dabrafenib plus trametinib across clinical trials in BRAF-mutant cancers. [Editorial Material]

Huang, Jiali Carrie and Emran, Abdullah Al and Endaya, Justine Moreno and McCaughan, Geoffrey W. and Gorrell, Mark D. and Zhang, Hui Emma DPP9: Comprehensive In Silico Analyses of Loss of Function Gene Variants and Associated Gene Expression Signatures in Human Hepatocellular Carcinoma. Cancers (2021), 13 (7) p. 1637. ISSN 2072-6694

Hamid, O. and Robert, C. and Daud, A. and Hodi, F.S. and Hwu, W.J. and Kefford, R. and Wolchok, J.D. and Hersey, P. and Joseph, R. and Weber, J.S. and Dronca, R. and Mitchell, T.C. and Patnaik, A. and Zarour, H.M. and Joshua, A.M. and Zhao, Q. and Jensen, E. and Ahsan, S. and Ibrahim, N. and Ribas, A. Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001. Annals of Oncology (2019), 30 (4) pp. 582-588. ISSN 09237534

Hamid, O. and Robert, C. and Daud, A. and Hodi, F.S. and Hwu, W.J. and Kefford, R. and Wolchok, J.D. and Hersey, P. and Joseph, R. and Weber, J.S. and Dronca, R. and Mitchell, T.C. and Patnaik, A. and Zarour, H.M. and Joshua, A.M. and Zhao, Q. and Jensen, E. and Ahsan, S. and Ibrahim, N. and Ribas, A. Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001. Annals of Oncology (2019), 30 (4) pp. 582-588. ISSN 09237534

Hersey, Peter and Tiffen, Jessamy C and Gallagher, Stuart J Shedding light on dabrafenib-induced fevers in patients with melanoma. The Lancet Oncology (2019), 20 (12) pp. 1637-1638. ISSN 14702045

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Lim, Su Yin and Alavi, Sara and Ming, Zizhen and Shklovskaya, Elena and Fung, Carina and Stewart, Ashleigh and Rizos, Helen Melanoma Cell State-Specific Responses to TNFα. Biomedicines (2021), 9 (6) p. 605. ISSN 2227-9059

Lee, Jenny H. and Shklovskaya, Elena and Lim, Su Yin and Carlino, Matteo S. and Menzies, Alexander M. and Stewart, Ashleigh and Pedersen, Bernadette and Irvine, Malama and Alavi, Sara and Yang, Jean Y. H. and Strbenac, Dario and Saw, Robyn P. M. and Thompson, John F. and Wilmott, James S. and Scolyer, Richard A. and Long, Georgina V. and Kefford, Richard F. and Rizos, Helen Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition. Nature Communications (2020), 11 (1) ISSN 2041-1723

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Madorsky Rowdo, Florencia and Barón, Antonela and Gallagher, Stuart and Hersey, Peter and Emran, Abdullah and Von Euw, Erika and Barrio, María Marcela and Mordoh, José Epigenetic inhibitors eliminate senescent melanoma BRAFV600E cells that survive long‑term BRAF inhibition. International Journal of Oncology (2020), ISSN 1019-6439

McGuire, Helen M. and Shklovskaya, Elena and Edwards, Jarem and Trevillian, Paul R. and McCaughan, Geoffrey W. and Bertolino, Patrick and McKenzie, Catriona and Gourlay, Ralph and Gallagher, Stuart J. and Fazekas de St. Groth, Barbara and Hersey, Peter Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report. Cancer Immunology, Immunotherapy (2018), 67 (4) pp. 563-573. ISSN 0340-7004

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Punnia-Moorthy, Gaya and Hersey, Peter and Emran, Abdullah Al and Tiffen, Jessamy Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers. [Review]

Pirozyan, Mehdi R. and McGuire, Helen M. and Emran, Abdullah Al and Tseng, Hsin-Yi and Tiffen, Jessamy C. and Lee, Jenny H. and Carlino, Matteo S. and Menzies, Alexander M. and Long, Georgina V. and Scolyer, Richard A. and Fazekas de St Groth, Barbara and Hersey, Peter Pretreatment Innate Cell Populations and CD4 T Cells in Blood Are Associated With Response to Immune Checkpoint Blockade in Melanoma Patients. Frontiers in Immunology (2020), 11 ISSN 1664-3224

Parikh, Victoria N. and Caleshu, Colleen and Reuter, Chloe and Lazzeroni, Laura C. and Ingles, Jodie and Garcia, John and McCaleb, Kristen and Adesiyun, Tolulope and Sedaghat-Hamedani, Farbod and Kumar, Saurabh and Graw, Sharon and Gigli, Marta and Stolfo, Davide and Dal Ferro, Matteo and Ing, Alexander Y. and Nussbaum, Robert and Funke, Birgit and Wheeler, Matthew T. and Hershberger, Ray E. and Cook, Stuart and Steinmetz, Lars M. and Lakdawala, Neal K. and Taylor, Matthew R.G. and Mestroni, Luisa and Merlo, Marco and Sinagra, Gianfranco and Semsarian, Christopher and Meder, Benjamin and Judge, Daniel P. and Ashley, Euan Regional Variation in RBM20 Causes a Highly Penetrant Arrhythmogenic Cardiomyopathy. Circulation: Heart Failure (2019), 12 (3) ISSN 1941-3289

Pirozyan, Mehdi R and Nguyen, Nam and Cameron, Barbara and Luciani, Fabio and Bull, Rowena A and Zekry, Amany and Lloyd, Andrew R Chemokine-Regulated Recruitment of Antigen-Specific T-Cell Subpopulations to the Liver in Acute and Chronic Hepatitis C Infection. The Journal of Infectious Diseases (2018), 219 (9) pp. 1430-1438. ISSN 0022-1899

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Robert, Caroline and Hwu, Wen-Jen and Hamid, Omid and Ribas, Antoni and Weber, Jeffrey S. and Daud, Adil I. and Hodi, F. Stephen and Wolchok, Jedd D. and Mitchell, Tara C. and Hersey, Peter and Dronca, Roxana and Joseph, Richard W. and Boutros, Celine and Min, Le and Long, Georgina V. and Schachter, Jacob and Puzanov, Igor and Dummer, Reinhard and Lin, Jianxin and Ibrahim, Nageatte and Diede, Scott J. and Carlino, Matteo S. and Joshua, Anthony M. Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma. European Journal of Cancer (2021), 144 pp. 182-191. ISSN 09598049

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Strub, Thomas and Ghiraldini, Flavia G. and Carcamo, Saul and Li, Man and Wroblewska, Aleksandra and Singh, Rajendra and Goldberg, Matthew S. and Hasson, Dan and Wang, Zichen and Gallagher, Stuart J. and Hersey, Peter and Ma’ayan, Avi and Long, Georgina V. and Scolyer, Richard A. and Brown, Brian and Zheng, Bin and Bernstein, Emily SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling. Nature Communications (2018), 9 (1) ISSN 2041-1723

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Tseng, Hsin‐Yi and Dreyer, Jan and Emran, Abdullah Al and Gunatilake, Dilini and Pirozyan, Mehdi and Cullinane, Carleen and Dutton‐Regester, Ken and Rizos, Helen and Hayward, Nicholas K. and McArthur, Grant and Hersey, Peter and Tiffen, Jessamy and Gallagher, Stuart Co‐targeting bromodomain and extra‐terminal proteins and MCL1 induces synergistic cell death in melanoma. International Journal of Cancer (2020), 147 (8) pp. 2176-2189. ISSN 0020-7136

Tiffen, Jessamy and Gallagher, Stuart J. and Filipp, Fabian and Gunatilake, Dilini and Emran, Abdullah Al and Cullinane, Carleen and Dutton-Register, Ken and Aoude, Lauren and Hayward, Nick and Chatterjee, Aniruddha and Rodger, Euan J. and Eccles, Michael R. and Hersey, Peter EZH2 Cooperates with DNA Methylation to Downregulate Key Tumor Suppressors and IFN Gene Signatures in Melanoma. Journal of Investigative Dermatology (2020), 140 (12) 2442-2454.e5. ISSN 0022202X

Torrano, Joachim and Al Emran, Abdullah and Hammerlindl, Heinz and Schaider, Helmut Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming. Clinical Epigenetics (2019), 11 (1) ISSN 1868-7075