Mechanisms, biomarkers and targets for therapy in alcohol-associated liver injury: From Genetics to nutrition: Summary of the ISBRA 2018 symposium

Mechanisms, biomarkers and targets for therapy in alcohol-associated liver injury: From Genetics to nutrition: Summary of the ISBRA 2018 symposium.

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Item Type: Article
Status: Published
Official URL: https://doi.org/10.1016/j.alcohol.2019.05.004
Journal or Publication Title: Alcohol
Volume: 83
Page Range: pp. 105-114
Date: 2020
Divisions: Alcoholic Liver Disease
Depositing User: General Admin
Identification Number: 10.1016/j.alcohol.2019.05.004
ISSN: 07418329
Date Deposited: 04 Jan 2021 03:41
Abstract:

The symposium “Mechanisms, Biomarkers and Targets for Therapy in Alcohol-associated Liver Injury: From Genetics to Nutrition” was held at the 19th Congress of International Society for Biomedical Research on Alcoholism on September 13th, 2018 in Kyoto, Japan. The goal of the symposium was to discuss the importance of genetics and nutrition in alcoholic liver disease (ALD) development from mechanistic and therapeutic perspectives. The following is a summary of this session addressing the gene polymorphisms in ALD, the role of zinc in gut–liver axis perturbations associated with ALD, highlighting the importance of dietary fat in ALD pathogenesis, the hepatic n6 and n3 PUFA oxylipin pattern associated with ethanol-induced liver injury, and finally deliberating on new biomarkers for alcoholic hepatitis and their implications for diagnosis and therapy. This summary of the symposium will benefit junior and senior faculty currently investigating alcohol-induced organ pathology as well as undergraduate, graduate, and post-graduate students and fellows.

Creators:
Creators
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Kirpich, Irina A.
UNSPECIFIED
Warner, Dennis R.
UNSPECIFIED
Feng, Wenke
UNSPECIFIED
Joshi-Barve, Swati
UNSPECIFIED
McClain, Craig J.
UNSPECIFIED
Seth, Devanshi
UNSPECIFIED
Zhong, Wei
UNSPECIFIED
Zhou, Zhanxiang
UNSPECIFIED
Osna, Natalia A.
UNSPECIFIED
Kharbanda, Kusum K.
UNSPECIFIED
Last Modified: 04 Jan 2021 03:41
URI: https://eprints.centenary.org.au/id/eprint/733

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