The lymphoid cell network in the skin

The lymphoid cell network in the skin.

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Item Type: Article
Status: Published
Official URL:
Journal or Publication Title: Immunology and Cell Biology
Volume: 96
Number: 5
Page Range: pp. 485-496
Date: 2018
Divisions: Immune Imaging
Depositing User: General Admin
Identification Number: 10.1111/imcb.12026
ISSN: 08189641
Date Deposited: 04 Jan 2021 04:31

Cutaneous immunity represents a crucial component of the mammalian immune response. The presence of a large array of commensal microorganisms along with a myriad of environmental stresses necessitates constant immuno‐surveillance of the tissue. To achieve a perfect balance between immune‐tolerance and immune‐activation, the skin harbors strategically localized immune cell populations that modulate these responses. To maintain homeostasis, innate and adaptive immune cells assimilate microenvironmental cues and coordinate cellular and molecular functions in a spatiotemporal manner. The role of lymphoid cells in cutaneous immunity is gaining much appreciation due to their important roles in regulating skin health and pathology. In this review, we aim to highlight the recent advances in the field of cutaneous lymphoid biology.

Tikoo, Shweta
Jain, Rohit
Kurz, Angela RM
Weninger, Wolfgang
Last Modified: 04 Jan 2021 04:31

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