Daily Step Count as a Simple Marker of Disease Severity in Hypertrophic Cardiomyopathy

Daily Step Count as a Simple Marker of Disease Severity in Hypertrophic Cardiomyopathy.

Full text not available from this repository.
Item Type: Article
Status: Published
Official URL: https://doi.org/10.1016/j.hlc.2017.12.012
Journal or Publication Title: Heart, Lung and Circulation
Volume: 27
Number: 6
Page Range: pp. 752-755
Date: 2018
Divisions: Cardio Genomics
Molecular Cardiology
Depositing User: General Admin
Identification Number: 10.1016/j.hlc.2017.12.012
ISSN: 14439506
Date Deposited: 03 Jan 2021 23:02

Background: Individuals with hypertrophic cardiomyopathy (HCM) may be asymptomatic or display activity-limiting symptoms. A common cause of symptoms is left ventricular outflow tract obstruction (LVOTO), which may impact the individuals' ability to undertake physical activity. This study sought to examine daily step count as a potential marker of exercise capacity, which may represent a proxy marker of disease severity in HCM.

Methods: A cross-sectional study of 63 HCM patients was conducted from March to November 2015. Participants wore an ActiGraph GT3X+ (Pensacola, Florida, USA) accelerometer for 7 days. Minutes per day of light, moderate and vigorous physical activity and step count were calculated, and those with LVOTO were compared to those without. Similarly, those with good functional capacity (New York Heart Association; NYHA class I) were compared to those with NYHA class II-IV.

Results: The majority of HCM patients were male (n=45, 71%) with mean age of 48.8±14.9years. Hypertrophic cardiomyopathy patients with history of LVOTO and those NYHA class II-IV took significantly fewer steps per day (LV obstruction: 5527±2370 versus 7027±2095, p=0.01 and NYHA: 5346±1898 versus 6801±2339, p=0.03). No differences were observed across the different intensities of physical activity.

Conclusions: Measurement of daily step count may be a useful and simple tool to determine exercise capacity and provide an indicator of disease severity in individuals with HCM.

Keywords: Accelerometry; Hypertrophic cardiomyopathy; Step count.

Copyright © 2018 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

Sweeting, Joanna
Ingles, Jodie
Ball, Kylie
Semsarian, Christopher
Last Modified: 03 Jan 2021 23:02
URI: https://eprints.centenary.org.au/id/eprint/495

Actions (login required)

View Item View Item