Sudden cardiac death: an update

Sudden cardiac death: an update.

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Item Type: Article
Status: Published
Official URL:
Journal or Publication Title: Internal Medicine Journal
Volume: 49
Number: 7
Page Range: pp. 826-833
Date: 2019
Divisions: Molecular Cardiology
Depositing User: General Admin
Identification Number: 10.1111/imj.14359
ISSN: 1444-0903
Date Deposited: 21 Dec 2020 23:00

Sudden cardiac death (SCD) is a devastating and all too common result of both acquired and genetic heart diseases. The profound sadness endured by families is compounded by the risk many of these deaths confer upon surviving relatives. For those with known cardiac disease, disease-specific therapy and risk stratification are key to reducing sudden death. For families of a SCD victim, uncovering a definitive cause of death can help relieve the agonising uncertainty and is a vital first step in screening surviving relatives and instituting therapy to reduce SCD risk. Increasing knowledge about the molecular mechanisms and genetic drivers of malignant arrhythmias in the diverse clinical entities that can cause SCD is vital if we are to optimise risk stratification and personalise patient care. Advances in diagnostic tools, disease-specific therapy and defibrillator technology are improving outcomes for patients and their families but there is still much progress to be made.

Keywords: cardiomyopathy; implantable cardiac defibrillator; ischaemic heart disease; primary arrhythmia syndrome; sudden cardiac death; sudden unexplained death.

© 2019 Royal Australasian College of Physicians.

Isbister, Julia
Semsarian, Christopher
Last Modified: 21 Dec 2020 23:00

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