Intron retention: importance, challenges, and opportunities

Intron retention: importance, challenges, and opportunities.

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Item Type: Article
Official URL:
Journal or Publication Title: Trends in Genetics
Volume: 38
Number: 8
Page Range: pp. 789-792
Date: 21 April 2022
Divisions: Epigenetics and RNA Biology
Gene and Stem Cell Therapy
Depositing User: General Admin
Identification Number: 10.1016/j.tig.2022.03.017
ISSN: 01689525
Date Deposited: 08 Jan 2023 22:46

Recent landmark discoveries have underpinned the physiological importance of intron retention (IR) across multiple domains of life and revealed an unexpected breath of functions in a large variety of biological processes. Despite significant progress in the field, some challenges remain. Once solved, opportunities will arise for discovering more functions of IR.

Keywords: RNA processing; alternative splicing; epi-transcriptomics; intron retaining transcripts; splicing regulation.

Wong, Justin J.-L.
Schmitz, Ulf
Last Modified: 08 Jan 2023 22:46

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